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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75549289d4a975ec406cd6c156a60d92062788137871e2ea518958d49520754' 
  AND token = '+d4RFlBE2R3YZ26zc3yyNcBKMKkKUuGSsxB8TSPzNDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}