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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754be068693064a3657c2dd46d27ca72577cb5ecbbf0d6999c69e381117bfd58' 
  AND token = '/LGCybr09DkyeEUtpTNdep2L3na9C3QJk8vi6l2l4oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}