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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c52d1925a72614c9b5638161696231353accf50419cd916ffc68c776c3acec6' 
  AND token = 'dMW72BrgPbUQ26JQNti8mB/I8nz6aoU9H+9WELtkAOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}