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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ae4f49ebd2fdd39f972a526a3f02de0c1ab82616e664141eb05ef97316364e9' 
  AND token = 'ZJDd4cGfjgSmcUf/HXwgJleX1La2R7uHQjaMd/JLzs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}