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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52355af4a39a00cfccbb80949a1b4ec28f44e50d612dfa6da3cffa75c754a1c' 
  AND token = 'w1GTrW2V/4kjbfUsomH57ZV+czn1ENQNJSZ6xxXC0VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}