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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49efae98a95df878aad3809db4feaee2d280cfb01d0eca650d40e8066817532' 
  AND token = '1MkDhjh/EEo6nM2Vpu+0Zs5Q5IJWkxf1d4uLyqNF4dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}