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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0777c862fa365e57a8917cb9503dfddc3941b14e74ad441259dd6b2dd829da4b' 
  AND token = 'TRWXbaZiKbVU4/U2iHlUQX4x/6JGTpM9IwDCMIxDp1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}