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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd180225b8eff38c70064bde712c68da02ce68f93bc810456ed552d80f8e881' 
  AND token = 'EfaDMOlQI+j9e8Xmf9gth6Hx47zwAENmaqGdbQ/L5+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}