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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99cef0c15c294ed786bf14be6a41c48d49655c914e05a0f33d8229c449774eff' 
  AND token = 'X4QFWBIEeasqvZkQhYRvgvEF9BhtfSagak8BX33nZP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}