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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c723657db46e5e88d5bf21f660dc30c5832434cd4cc2b822860a6570ba7216' 
  AND token = '+p1dTdgIir+rXf3GFR91e5fBpNYVGcsa/xn2ISVMoPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}