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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8672186b8f765c3a2eaa1cb21c5bec370ca866670187c86fdc6229ab9d9a6a' 
  AND token = 'QRdtgS/krUQ5Y+jHeUDOK/hCrOAdEu/l2pDibnyQvyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}