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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7e4a8109e22e16b729a6b0c485be503caae3a3acaeb8a3a80ff615907df7f1' 
  AND token = 'XCO14ksHn+u57oq4e+mPxfTImp0tYyYt+XuMwzqt1Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}