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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14395bfd5f56f04a10d01b88d86770f1b5c2b59f8cdaf60b6d3efa082fcb56bb' 
  AND token = '6zSPpD01MxbIoV2Hu7acZdu4gVgx0iZw+RPhHgTpXY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}