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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572b58bfb13f3bce2016ccc1684516c4563a57123ea8b4c765e204398d8841e3' 
  AND token = 'n0AAFVNqZ5uzfEL8MyVGwjzrbNEXR/od17Dz7xk7M+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}