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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae45a3d651f259c007e503ece7603622cfb942094489fc054f788247625fc620' 
  AND token = 'N7/0AbIUW6T9p7lRIDS4alua6W8DRzH8DhTP+7DcxS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}