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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd86274e27f1552cacc83494f84005740fb4999ce02f8ce1dbce4eeeb0e902474' 
  AND token = 'e+dWa7ab7VV11KW0XlxAZ2tHXPu4zt593hrKtwHDSHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}