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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0cc75aa06b0766d503622d56b84d0aadc25e1ebd739f572a863448c674739e' 
  AND token = 'D+sI0t4Ibl0TwFFgUAMH+lvbV9r4QHU5Za2HUPgmmeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}