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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1c5803e95a5072420074620c36621d9f0179cbd046d6426339009ce5b56cec' 
  AND token = 'vjQ4M78J9EEB7XgpOD9kimDhxFErJm6H4rlCDAY6tq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}