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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efdb3071a65f27c898913111a9ca89e2d9f60ceccbd5d43b8fa65b64c99ea1f' 
  AND token = '3XMtb0UTjpNKeTkuXTg2yl8mVIa9gLelnDEdZU7t+FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}