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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27d77dd144614e741b508e11e1ac93e7155c1f1f2602c1fc97a6d08c6611d2c' 
  AND token = 'WV6vNmWnxSnBNR1lg2RQk0feU/uAAo+WrHrq4xHdzSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}