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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caec351ccc9447e44d13dc5edc6d6758adaec8ead12d059195072a846ccdfd64' 
  AND token = 'hzpEB8/Eo+4vvk6QyTgCLvS5nP9CEzbZFMfcqjcA4Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}