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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a256788a9e56f214441dad40cbb0d68ddea64e6b8189d4626445a556d75916fb' 
  AND token = 'VA5r7uC+RETxpIwh6nwJr3PMT1CGTFQMsQykI/HJSeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}