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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e807159f8873c4d07b495fe6f81a3b17edd9836b22d2e3bd5edd03122adaa745' 
  AND token = 'Y+oO8LhO2IznUuHRtbu6veIItQJ7oRx6xRiD2sbbRIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}