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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77effebce72b5f9ff5aedbceb5f30f12e5edb4ad4a53094b2dca0fa4d0f1c212' 
  AND token = '2iERRap64vcgyyuyo9o+MayBESCX1WSZinR473U5EQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}