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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8c04b6222f31414bacc3a1bbe52ce996f74fa67f4f001e3dc8eaaeea3b50ca' 
  AND token = 'o25qMC+hMxd9Prwi0l4RNNSAM4JS7JOE4d3B1GLCZuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}