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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a41854cd79e0792496d3ca5034ec5678d25feb2e4ea6f9995167f45a9c4e942' 
  AND token = 'aeasRmvhzxiOpzO0vI32n8tgKH1XNPquwmw6iXoueh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}