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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7bf0f506a341f0c102fffb1d0e3a47adad0fce186feee58ee36911f5fad2a3b' 
  AND token = 'xCTltO3ET0YvT7/xcIDThZcjaZWifzBaMg3/4d2fOGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}