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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a91b3da023afb9e3ebb9d54c69b02b678909f963d4e9e247c7a7d408dcf02f8' 
  AND token = 'cS38q5nar+CFF66swN9cOGR2B8F4ff7a6Y7Dz+eq+nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}