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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afed0e2aad820c31bd1349736825da0cbe4f9b0c597d019bbd02739a5e9e953d' 
  AND token = 'gG71R8NiCi2IKs9d9sOV3w9yKNEGhpss3dmMPh08Lck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}