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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e60b2ca551b3212f4a1884d688d8139ffd396942d85566e8db33930ebfdc249' 
  AND token = '3ysn/48+2Q0yrl5TlEI72H95yy7hADj8RRc9ACDEXQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}