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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8b7f9223c6b16ad1afa0e098a46a1494f66a1eb0403d311ed7d269dcec894e' 
  AND token = 'WNQSbXiv3MxA9+pOSyR9zXBjvJ4FXDwx1yq3CLwyhjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}