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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '841ab665709e4750305f8fb1db6ef021e13cfaa78c32119b7e6ae7c73706db37' 
  AND token = 'jqTx3Fp9j3WSNzSqL6e4VzaNzyUoNMp+sgSI3AUA8ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}