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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ffec895144d108b4ac2b5dd6ce8fb528dc56b01aef1dfb2248f6a908d8e855b' 
  AND token = 'yPWLW+EjF6Mk69ZnUJt0KNuABm7SIEYcPF+sQnbTWV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}