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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99b8e7b3cb6667870d38600f890f6fe584f2232386962e8a8ba1d59c44465c9f' 
  AND token = 'VenMJipVQjsUyIUqml/Cx0crfphLaml8V47uOJuqSaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}