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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0f38897bc7711ff78a770cf2da03a8f5270d596c3a33ab0edf294f5da6acc3' 
  AND token = 'QsPmFaw0BetodgGUVbHf49aDe2IuIgsOsfUyx7SDOAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}