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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f18cbe98d1557041d942ad97e8d3ea9d0d6f749dc9a967347a3b40902a6a5fd' 
  AND token = 'fDV+7AIwnIPjl7ZD999xF3tdx9I8Zhgym2GU87E/2zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}