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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222ee904666b1a9bb35902048a434d257ae85efcb25dd8559f8eba8771bc16db' 
  AND token = '+C+3PSDW7knsZVAhHmtPSNSw3L39tHAinqlSsj56Y5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}