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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42973122bed5bf5f9ef1a8c82d2dbe278482b12d0ab971f214f8481b6d74ae9e' 
  AND token = 'SJyF/M6A2XIoT3UbzUdQuikZRa3z6GNH04+KFRFeonU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}