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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eea2e5a2a47b11717b6c5b44d6e6e919eb05ae09cb706fa5438d4a08801b0039' 
  AND token = '72uY7f642pMIxJn0mTD+F4yu45hjNDn/cnCRGJ0qXy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}