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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97d0af4ab451e96e1dc1072f7a0eca4230d647231d448e732eb780fddae4ce1' 
  AND token = 'S1FPyi9411LgIoTX5eBPS3pfIhMxsdzZnkCzq1xkUKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}