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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcc5c816270322567f13e25bf5b84352514d013867cb4f3137cfc51a5efe4649' 
  AND token = 'o+XGw5UzOWHMr1bqFyvwdiaHFp0UNq8yGGAyZXZZL2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}