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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af18350c80cae38b2e63d8a7ebaa7b160578f446f977d1c9908a7a6459874370' 
  AND token = '83Y0iAV+j9p/HLbWLvGSyvTjVBhF94HEvBMcS0RXhys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}