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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6e65a503db0feb38b24c6ad11794f8302f28ff84e0b4da50c0a0d3070ffd6b' 
  AND token = 'HQxbkvs46NAZS3lUoby5qQ70qM9o9wj1CUWsUBJv+ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}