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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9253a902f81eca7ea2867f9b2e1ed8d680f03e788ceef544f533bd6aaed3e85d' 
  AND token = 'PVgPo8RII5ILZiwnJdoKiFhZSGOiQaBjspQILPI1Src=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}