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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6d9b24d7d31799c1f228ce7f358184a574125ada0e1c0191e2fd449f9dd47c' 
  AND token = 'npVU8EaLnigypg3N0pa63SbxgP7RxYBMNgcCqeBLAJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}