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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dbbc9b53e49b4d12898a5d29272290761794b2edb6f7c3c45df244028ee4647' 
  AND token = 'AIOKSaQdo8RvSt/ThOK1HUV8TJqw/uPt3+xD5iwbhMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}