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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425306f3e15a1686cb6ae68c3057ab18e07c5a6750b69c9f17ff5678f37fdc5b' 
  AND token = 'dVA3NS4ynYNlY1SvUNfIXrVcfizqfy1a3v1yC2I2qGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}