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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472921c75b2e82c914967dd7ce33f308910c86cd97c842174a92d1958b2b20b9' 
  AND token = 'LC1DhvMwPCZ9KrPHHnhE/5eZWYupDSfiPX3Zgy0mlZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}