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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '311442572b53fa22e083d5e6d74a350d8e5852cd027781adfba4f026fb50f13b' 
  AND token = 'NtVBKE1AYgLs2Krq3UmVWet0fpuDNCsMCIcUkkV5/PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}