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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81be66595cb7e9cf74dab35c596a0f16fc5c48b8994ed04ae68c62687140a3c' 
  AND token = 'iuHIWuYzBUGHaRM0AX9p91u2TiVSzC+L8sCRYhjQ14k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}